Isolated nucleic acid molecule coding for tumor rejection...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) C07K 7/06 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2201161

A new family of tumor rejection antigen precursors, and the nucleic acid molecules which code for them, are disclosed. These tumor rejection antigen precursors are referred to as DAGE tumor rejection antigen precursors, and the nucleic acid molecules which code for them are referred to as GAGE coding molecules. Various diagnostic and therapeutic uses of the coding sequences and the tumor rejection antigens, and their precursor molecules are described.

L'invention porte sur une nouvelle famille de précurseurs d'antigènes de rejet tumoral et sur des molécules d'acide nucléique codant pour eux. Lesdits précurseurs sont désignés sous l'appellation de précurseurs d'antigènes de rejet tumoral DAGE, et les molécules d'acide nucléique codant pour eux, sous l'appellation de molécules de codage GAGE. L'invention porte également sur différentes utilisations à caractère diagnostique et thérapeutique des séquences de codage et des antigènes de rejet tumoral et sur leurs molécules précurseurs.

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