Isolated nucleic acid molecule encoding peptides which form...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 35/14 (2006.01) A61K 39/00 (2006.01) C07K 14/47 (2006.01) C07K 14/74 (2006.01) C12N 5/10 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2213001

A family of tumor rejection antigen precursors, and the nucleic acid molecules which code for them, are disclosed. These tumor rejection antigen precursors are referred to as BAGE tumor rejection antigen precursors, and the nucleic acid molecules which code for them are referred to as BAGE coding molecules. Various diagnostic and therapeutic uses of the coding sequences and the tumor rejection antigen precursor molecules are described.

On décrit une famille de précurseurs d'antigène de rejet tumoral, ainsi que les molécules d'acides nucléiques codant pour ceux-ci. On se réfère aux précurseurs d'antigène de rejet tumoral comme à des précurseurs d'antigène BAGE, ainsi qu'aux molécules d'acide nucléique codant pour ces précurseurs comme à des molécules codant pour BAGE. On décrit également différentes utilisations diagnostiques et thérapeutiques de ces séquences codantes, ainsi que les molécules du précurseur d'antigène de rejet tumoral.

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