C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/00 (2006.01) C07H 21/04 (2006.01) C07K 16/00 (2006.01) C12P 21/06 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2565014
Provided herein are novel nucleic acid and amino acids sequences of a phosphoprotein derived from a Guinea pig. Methods and compositions for modulating the phosphorylation of the novel protein in a dopaminergic signaling pathway are also provided. Compounds identified by the disclosed methods may be used to treat disorders characterized by a aberrant or dysfunctional intracellular signaling pathway regulated by DARPP-32.
L'invention concerne de nouvelles séquences d'acides nucléiques et d'acides aminés d'une phophoprotéine dérivée d'un cobaye. Elle concerne également des procédés et compositions permettant de moduler la phosphorylation de la nouvelle protéine dans une voie de signalisation dopaminergique. Des composés identifiés par ces procédés peuvent être utilisés pour traiter des troubles se caractérisant par une voie de signalisation intracellulaire aberrante ou dysfonctionnelle régulée par DARPP-32.
Acton Paul J.
Brandish Philip E.
Wei Nan
Merck And Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
LandOfFree
Isolated nucleic acid molecules encoding a novel... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Isolated nucleic acid molecules encoding a novel..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Isolated nucleic acid molecules encoding a novel... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1654593