Isolated peptides having phospholipase inhibitory activity

Details Isolated peptides having phospholipase inhibitory activity Isolated peptides having phospholipase inhibitory activity

C - Chemistry, Metallurgy

12

N

C12N 15/55 (2006.01) C07K 14/37 (2006.01) C12N 1/15 (2006.01) C12N 9/00 (2006.01) C12N 9/20 (2006.01) C12N 15/80 (2006.01) C12P 21/00 (2006.01)

Patent

CA 2722994

The invention provides C-terminal peptides from lipases having phospholipase inhibitory activity, polypeptides comprising phospholipase inhibitory activity and lipases capable of being inhibited by the isolated peptides and/or polypeptides comprising phospholipase inhibitory activity. The invention also relates to nucleic acid constructs, recombinant expression vectors, and recombinant host cells comprising the polynucleotides as well as methods for producing and using the peptides and the polypeptides having lipase inhibitory activity.

L'invention concerne des peptides C-terminaux de lipases qui présentent une activité d'inhibition des phospholipases, des polypeptides présentant une activité d'inhibition des phospholipases et des lipases pouvant être inhibées par les peptides isolés et/ou les polypeptides comprenant une activité d'inhibition des phospholipases. L'invention concerne également des constructions d'acide nucléique, des vecteurs d'expression recombinants, et des cellules hôtes recombinantes comprenant les polynucléotides ainsi que des procédés de production et d'utilisation des peptides et des polypeptides présentant une activité d'inhibition des phospholipases.

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