Isolated peptides which complex with hla-cw*16 molecules,...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) C07K 4/00 (2006.01) C07K 7/06 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) G01N 33/554 (2006.01) A61K 38/00 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2264563

The invention involves the identification of peptides which complex with HLA-Cw*16 molecules, and which may then provoke lysis of the cells to which they bind, by cytolytic T cells. Diagnostic and therapeutic uses are described.

L'invention porte sur l'identification de peptides qui forment un complexe avec les molécules HLA-Cw*16, et qui peuvent alors provoquer une lyse, par les lymphocytes T cytolytiques, des cellules auxquelles elles sont liées. L'invention concerne également des applications diagnostiques et thËrapeutiques.

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