Isolated polynucleotide sequences encoding a fertility...

A - Human Necessities – 61 – K

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Details

A61K 39/00 (2006.01) C07H 21/04 (2006.01) C07K 1/00 (2006.01) C07K 14/575 (2006.01) C12N 15/09 (2006.01)

Patent

CA 2415348

The present invention provides an isolated polynucleotide sequence and amino acid sequence for a bovine fertility associated antigen (FAA), methods of producing recombinant bovine FAA protein; methods of increasing the stability of the plasma membrane, acrosome, and/or other portions of a sperm cell by mixing with FAA and/or recombinant FAA protein(s); and increasing fertility of bulls by mixing sperm cells with FAA and/or recombinant FAA protein(s).

La présente invention concerne une séquence de polynucléotide isolé et une séquence d'acide aminé codant un antigène bovin associé à la fertilité (AAF), des procédés de production de la protéine AAF bovine recombinante, et des procédés permettant d'augmenter la stabilité de la membrane plasmique, de l'acrosome et/ou d'autres parties d'une cellule spermatique par mélange avec une ou des protéine(s) AAF et/ou AAF recombinantes, et d'augmenter la fertilité des taureaux en mélangeant les cellules spermatiques avec une ou des protéine(s) AAF et/ou AAF recombinantes.

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