Isolated polynucleotides and methods of promoting a...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/31 (2006.01) C12N 15/113 (2010.01) C07K 14/37 (2006.01) C07K 14/38 (2006.01) C12N 1/14 (2006.01) C12N 15/80 (2006.01) C12P 7/48 (2006.01)

Patent

CA 2485687

The invention includes isolated polynucleotide molecules that are differentially expressed in a native fungus exhibiting a first morphology relative to the native fungus exhibiting a second morphology. The invention includes a method of enhancing a bioprocess utilizing a fungus. A transformed fungus is produced by transforming a fungus with a recombinant polynucleotide molecule. The recombinant polynucleotide molecule contains an isolated polynucleotide sequence linked operably to a promoter. The polynucleotide sequence is expressed to promote a first morphology. The first morphology of the transformed fungus enhances a bioprocess relative to the bioprocess utilizing a second morphology.

L'invention concerne des molécules de polynucléotides isolées qui sont exprimées de manière différentielle dans un champignon naturel présentant une première morphologie par comparaison à un champignon naturel présentant une seconde morphologique. L'invention concerne également un procédé consistant à améliorer un bioprocédé au moyen d'un champignon. Ce procédé consiste à produire un champignon transformé, au moyen d'un processus de transformation comprenant l'utilisation d'une molécule polynucléotidique recombinée. Cette molécule polynucléotidique recombinée contient une séquence polynucléotidique isolée liée de manière fonctionnelle à un promoteur. L'expression de cette séquence polynucléotidique favorise la première morphologie. Cette première morphologie du champignon transformée permet d'améliorer un bioprocédé par rapport à un bioprocédé comprenant un champignon présentant la seconde morphologie.

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