Isolated vshk-1 receptor polypeptides and methods of use...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 14/72 (2006.01) C07K 16/28 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2349759

A new seven transmembrane receptor has been identified, and the amino acid and nucleotide sequence of the receptor are provided. The nucleotide sequence is useful to construct expression cassettes and vectors to produce host cells which are capable of expressing the receptor, its mutants, fragments, or fusions. Such polypeptides are useful for identifying new receptor binding agonists and antagonists.

L'invention concerne l'identification d'un nouveau récepteur heptatransmembranaire, et ses séquences d'acide aminé et de nucléotides. La séquence de nucléotides est utile pour construire des cassettes et des vecteurs d'expression, afin de produire des cellules hôtes capables d'exprimer le récepteur, ses mutants, ses fragments ou ses fusions. Ces polypeptides sont utiles pour identifier le nouveau récepteur se liant avec des agonistes et des antagonistes.

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