Isolating biological modulators from biodiverse gene...

Details Isolating biological modulators from biodiverse gene... Isolating biological modulators from biodiverse gene...

C - Chemistry, Metallurgy

12

N

C12N 15/63 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) C40B 20/00 (2006.01) C40B 30/06 (2006.01) C40B 40/02 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2721199

The present invention provides a method for identifying a modulator or mediator of a biological activity, which activity includes antigenicity and/or immunogenicity, said method comprising the steps of: (i) producing a gene fragment expression library derived from defined nucleotide sequence fragments; and (ii) assaying the expression library for at least an amino acid sequence derived from step (i) for a biological activity wherein that activity is different from any activity the amino acid sequence may have in its native environment.

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