C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/54 (2006.01) C12N 1/19 (2006.01) C12N 9/10 (2006.01) C12N 15/11 (2006.01) C12N 15/82 (2006.01) C12Q 1/02 (2006.01) C12Q 1/48 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2071486
2071486 9106673 PCTABS00005 A mutation defining a gene for the N.alpha.-acetyltransferase of yeast has been identified and cloned. Mutations in this gene have been constructed and used to produce cells which are substantially incapable of catalyzing N.alpha.-acetylation of protein. Such cells are valuable tools for determining the amino acid sequence of uncharacterized proteins. Such cells are also valuable tools for expressing a recombinant protein lacking an acetyl group at its .alpha.-amino group.
Lee Fang-Jen S.
Smith John A.
Gowling Lafleur Henderson Llp
The General Hospital Corporation
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