C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) C07H 21/00 (2006.01) C07K 14/735 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12P 21/02 (2006.01) C12P 21/08 (2006.01) C12Q 1/00 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2118329
The present invention relates to nucleic acid sequences encoding amino acid sequences of the .alpha., .beta., and .gamma. subunits of the high affinity receptor for immunoglobulin E, and for amino acid sequences of the subunits. The invention further relates to a method of producing the receptor by expressing cDNA for its .alpha., .beta., and .gamma. subunits in a host cell simultaneously. Aspects of the invention are methods and compositions to produce the human beta subunit, as well as to inhibit its function, thereby treating or preventing allergic reactions.
Department O. F. Health And Human Services The United States Of America Represented By The Secretary
Fetherstonhaugh & Co.
The United States Of America As Represented By The Department Of Health And Human Services
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