Isolation of escherichia coli heat-stable enterotoxin of...

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A61K 39/108 (2006.01) C07K 14/245 (2006.01) C12P 21/04 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1188986

ABSTRACT OF THE DISCLOSURE A heat-stable enterotoxin obtained from the Escherichia coli strain F11(P155) ATCC....... character- ized as the octadecapeptide H2N-Asn-Thr-Phe-Tyr-Cys-Cys- Glu-Leu-Cys-Cys-Asn-Pro-Pro-Cys-Ala-Ala-Gly-Tyr-COOH, and a process for preparing same in the substantially pure state. The substantially pure heat-stable enterotoxin is useful as an immunogenic agent in veterinary and in human medicine, and antiserum prepared therewith is useful as a reagent for determining the presence of said enterotoxin in biological fluids by immunochemical means.

376579

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