Isolation of fetal erythrocytes

Details Isolation of fetal erythrocytes Isolation of fetal erythrocytes

C - Chemistry, Metallurgy

12

N

C12N 5/08 (2006.01) A61K 35/18 (2006.01) C12N 1/06 (2006.01) C12N 5/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/483 (2006.01) G01N 33/49 (2006.01) G01N 33/50 (2006.01) G01N 33/555 (2006.01)

Patent

CA 2154460

A method for isolating nucleated fetal erythrocytes (NFEs) from a maternal blood sample by separating erythrocytes in the maternal blood sample from all other nucleated cells therein; and isolating NFEs from nonnucleated maternal erythrocytes. Preferably the maternal blood is peripheral maternal blood. The isolated NFEs can then be analyzed for genetic disorders and the like, such as by in situ hybridization.

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