Isolation of sperm cells from other biological materials...

G - Physics – 01 – N

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G01N 27/447 (2006.01)

Patent

CA 2506935

The present invention relates to cell separation using microfabricated devices (Figure 2). In particular, the present invention provides methods and devices for separation of sperm from biological materials, such as other cells and molecular species, in a cell mixture in a microfabricated device through the use of electroosmotic flow, electrophoretic mobility, pressure gradient, differential adhesion, and/or combinations thereof.

La présente invention concerne la séparation cellulaire au moyen de dispositifs microfabriqués. Notamment, cette invention a trait à des méthodes et des dispositifs de séparation du sperme d'autres matières biologiques, telles que d'autres cellules et espèces moléculaires, dans un mélange cellulaire d'un dispositif microfabriqué par le biais de l'utilisation d'un flux électro-osmotique, de la mobilité électrophorétique, d'un gradient de pression, d'une adhésion différentielle et/ou de combinaisons associées.

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