Isomeric dideoxynucleosides

Details Isomeric dideoxynucleosides Isomeric dideoxynucleosides

C - Chemistry, Metallurgy

07

D

167/202, 260/242

C07D 473/34 (2006.01) A61K 31/70 (2006.01) C07D 307/20 (2006.01) C07D 307/22 (2006.01) C07D 339/08 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01) C07D 473/00 (2006.01) C07H 13/00 (2006.01) C07H 13/12 (2006.01) C07H 19/16 (2006.01)

Patent

CA 2009658

KAN 4430/35 Abstract Compounds of the formula Image wherein A is 6-Amino-9H-purin-9-yl or 2-Amino-6-hydroxy-9H- purin-9-yl, wherein the amino group may be replaced by NHC(O)R and N=CHR3R4, and R is OH or OC(O)R1, wherein R1, R2, R3 and R4 is each independently straight or branched chain C1-20 alkyl, C1-l2 alkoxyalkyl, substituted or unsubstituted phenoxy-C1-4- alkyl, substituted or unsubstituted phenyl with the substituents selected from the group consisting of halogen, C1-4 alkoxy, nitro, hydroxy, carboxyl or alkylamino, and pharmaceutically acceptable salts thereof, are useful in the treatment of retroviral infections.

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