Isopropanolate of azithromycin and method of manufacturing

C - Chemistry – Metallurgy – 07 – H

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C07H 17/08 (2006.01) C07D 413/14 (2006.01) C07H 17/00 (2006.01)

Patent

CA 2422972

Azithromycin isopropanolate of the empirical formula azithromycin : [H2O]x: [isopropanol]y is obtained from the crystallization of azithromycin in isopropanol and water. The x and y values is confirmed by single X-ray diffraction determination. In one embodiment x=1.5 and y=0.25. In another embodiment x.75 and y=0.5.

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