Isoquinoline compounds having antiinfective activity

Details Isoquinoline compounds having antiinfective activity Isoquinoline compounds having antiinfective activity

C - Chemistry, Metallurgy

07

D

C07D 217/12 (2006.01) A61K 31/47 (2006.01) C07D 207/42 (2006.01) C07D 217/26 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/14 (2006.01) C07D 409/04 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/04 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2450625

Isoquinoline compounds having the formula where R1, R2, Y, m, n, and Z are as defined herein, bind to the minor groove of DNA and have antifungal and antibacterial activity.

L'invention concerne des composés isoquinoline selon la formule suivante, dans laquelle R?1¿, R?2¿, Y, m, n et Z sont tels que définis dans le descriptif, qui se lient au sillon mineur de l'ADN et qui ont une activité antifongique et antibactérienne.

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