Isoquinoline derivatives and drugs

Details Isoquinoline derivatives and drugs Isoquinoline derivatives and drugs

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) A61K 31/55 (2006.01) C07D 217/22 (2006.01) C07D 471/08 (2006.01) C07D 487/08 (2006.01)

Patent

CA 2245728

The invention relates to a compound of the following general formula [I] or a medicinally acceptable salt thereof, or a solvate thereof, (see formula I) wherein R1 represents alkyl, alkenyl, alkynyl, alkoxy, hydroxy, cyano, or halogen; R2 represents hydrogen, hydroxy, or halogen; R3 represents hydrogen, alkyl, or amidino; Ring A represents a 5 to 11-membered cyclic amino group which may be substituted, which cyclic amino group may be bridged between two carbon atoms in optional positions. The compound of this invention is useful for the prevention or treatment of cerebral tissue impairment due to the vasospasm following cerebral hemorrhage.

L'invention porte sur des composés de formule générale (I), leurs sels pharmacocompatibles et leurs solvates. Dans ladite formule, R<1> représente alkyle, alcényle, alcynyle, alcoxy, hydroxy, cyano, ou halogéno; R<2> représente, hydroxy, cyano, ou halogéno; R<3> représente, hydrogène, alkyle ou amidino; et A représente un amino cyclique à 5 à 11 chaînons, facultativement substitué, dans lequel deux atomes de carbone arbitraires peuvent former une liaison. Ces composés servent à la prévention et au traitement des lésions des tissus cérébraux dues à la vasoconstriction consécutive à une hémorragie cérébrale.

Affiliated with

Also associated with

Rating

Isoquinoline derivatives and drugs does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Isoquinoline derivatives and drugs, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Isoquinoline derivatives and drugs will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1982109