Isoquinoline derivatives and methods of use thereof

Details Isoquinoline derivatives and methods of use thereof Isoquinoline derivatives and methods of use thereof

A - Human Necessities

61

K

A61K 31/473 (2006.01) C07D 221/18 (2006.01)

Patent

CA 2557547

The present invention relates to Isoquinoline Derivatives, compositions comprising an effective amount of a Isoquinoline Derivative and methods for treating or preventing an inflammatory disease, a reperfusion injury, an ischemic condition, renal failure, diabetes, a diabetic complication, a vascular disease other than a cardiovascular disease, cardiovascular disease, reoxygenation injury resulting from organ transplantation, Parkinson's disease, or cancer, comprising administering to an animal in need thereof an effective amount of a Isoquinoline Derivative.

La présente invention concerne des dérivés d'isoquinoline, des compositions renfermant une dose efficace d'un dérivé d'isoquinoline et des méthodes de traitement ou de prévention de diverses pathologies maladies inflammatoires, lésion de reperfusion, état ischémique, défaillance rénale, diabète, complication liée au diabète, maladies vasculaires autres que cardio-vasculaires, maladies cardio-vasculaires, lésion de réoxygénation par suite de transplantation d'organes, maladie de Parkinson ou cancer consistant à administrer une dose efficace d'un dérivé d'isoquinoline à un animal qui en a besoin.

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