Isoquinoline derivatives and preparation thereof

Details Isoquinoline derivatives and preparation thereof Isoquinoline derivatives and preparation thereof

C - Chemistry, Metallurgy

07

D

260/286

C07D 217/20 (2006.01)

Patent

CA 1152998

A B S T R A C T The present invention relates to new 1-[1-(3,4-dimethoxy-phenyl) -3-amino-propyl]-6,7-dimethoxy-isoquinolines having the general formula I : Image I in which R1 represents a hydrogen atom or a methyl group ; and R2 represents an alkyl group having from 1 to 5 carbon atoms or a cycloalkyl group having from 5 to 7 carbon atoms, the alkyl or cycloalkyl group optionally being substituted by a hydroxy, phenyl or phenoxy group and the cycloalkyl group optionally being substituted by an alkyl group having from 1 to 5 carbon atoms, therapeutically acceptable salts thereof and a process preparation of the same. These compounds are useful in the cardiac and vascular fields.

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