Isoquinoline derivatives as inhibitors of rho-kinase

Details Isoquinoline derivatives as inhibitors of rho-kinase Isoquinoline derivatives as inhibitors of rho-kinase

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/4725 (2006.01) A61P 11/00 (2006.01) A61P 27/00 (2006.01) C07D 217/02 (2006.01) C07D 217/22 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2611295

The invention relates to 6-piperidinyl-substituted isoquinoline derivatives of the formula (I); useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.

L'invention concerne des dérivés d'isoquinoline 6-pipéridinyle substitués de formule (I); utilisés dans le traitement et/ou la prévention de maladies associées à la rho-kinase et/ou à la phosphorylation induite par la rhokinase de phosphatase à chaîne légère de myosine, et des compositions contenant ces composés.

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