C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/14 (2006.01) A61K 31/472 (2006.01) A61K 31/4725 (2006.01) A61P 19/02 (2006.01) C07D 217/24 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 401/10 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/04 (2006.01) C07D 405/06 (2006.01) C07D 405/14 (2006.01) C07D 413/06 (2006.01) C07D 521/00 (2006.01)
Patent
CA 2492019
This invention provides compounds defined by Formula I or a pharmaceutically acceptable salt thereof, wherein R1, Q, Y, R2, R3, R4, R5, and n are as defined in the specification ás MMP-13 enzyme inhibitors. The invention also provides pharmaceutical compositions comprising a compound of Formula I and the use of a compound of Formula I for the manufacture of a :medicament useful for treating osteoarthritis or rheumatrid arthritis.
L'invention concerne des composés définis par la formule (I), ou un sel pharmaceutiquement acceptable de ceux-ci, formule dans laquelle R?1¿, Q, Y, R?2¿, R?3¿, R?4¿, R?5¿ et n sont tels que définis dans la description, utilisés comme inhibiteurs de l'enzyme MMP-13. L'invention concerne également des compositions pharmaceutiques comprenant un composé de formule (I) et l'utilisation d'un composé de formule (I) pour la fabrication d'un médicament utilisé pour le traitement de l'arthrose ou de la polyarthrite rhumatoïde.
Bunker Amy Mae
Ortwine Daniel Fred
Smart & Biggar
Warner-Lambert Company Llc
LandOfFree
Isoquinoline derivatives as matrix metalloproteinase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Isoquinoline derivatives as matrix metalloproteinase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Isoquinoline derivatives as matrix metalloproteinase inhibitors will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1919898