Isoquinoline derivatives for the treatment of glaucoma or...

Details Isoquinoline derivatives for the treatment of glaucoma or... Isoquinoline derivatives for the treatment of glaucoma or...

C - Chemistry, Metallurgy

07

D

167/226, 260/281

C07D 217/24 (2006.01) A61K 31/47 (2006.01)

Patent

CA 2013167

ABSTRACT OF THE DISCLOSURE The use of isoquinoline derivatives for the treatment of glaucoma or ocular hypertension. The isoquinoline derivatives are of formula I Image wherein R1 is a hydrogen atom or a C1-C6 alkyl group and R2 is a C1-C6 alkyl group. The stability of the isoquinoline derivatives when used in the form of a solution is improved by incorporating therein compounds having a phenolic hydroxyl group and/or glycols serving as a stabilizer.

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