Isoquinolines derivatives as igf-1r inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 217/18 (2006.01) A61K 31/472 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07D 217/20 (2006.01)

Patent

CA 2621820

Compounds of the formula (I) were synthesized. They were found to down- regulate or inhibit the expression or function of the IGF-1 receptor.

On a synthétisé des composés ayant la formule (I). On a découvert que ces composés régulent vers le bas ou inhibent l'expression ou la fonction du récepteur IGF-1.

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