Isosorbide nitrates having vasodilating activity

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 493/04 (2006.01) A61K 31/34 (2006.01) A61P 9/08 (2006.01)

Patent

CA 2731574

The present invention relates to new 3-substituted 6-nitrooxy-hexahydrofuro [3,2- b]furane derivatives possessing a superior pharmacological activity in thrombosis and in coronary ischemia models.

Cette invention concerne de nouveaux dérivés 6-nitrooxy-hexahydrofuro[3,2- b]furane substitués en 3 ayant une activité pharmacologique supérieure dans les modèles de thrombose et dischémie des coronaires.

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