Isothiuronium salts

Details Isothiuronium salts Isothiuronium salts

C - Chemistry, Metallurgy

07

C

260/466.05, 260/

C07C 335/38 (2006.01) A61K 31/155 (2006.01) C07D 303/34 (2006.01) C07D 303/46 (2006.01)

Patent

CA 1301770

A b s t r a c t According to the present invention there are provided isothiuronium salts of the general Formula I Image /I/ /wherein R1 is C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-6 cycloalkyl, aralkyl or aryl , the said groups being optionally substituted by one or more hydroxy, mercapto and/or halogen; R2 stands for hydrogen, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl or C3-6 cycloalkyl; X represents an organic or inorganic anion/. The compounds and salts of the present invention can be prepared by reacting a compound of the general Formula II Image /II/ with an agent capable of introducing a R1 group. The compounds of the general Formula I exhibit antitumor and immunostimulant effect and are useful in therapy.

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