C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 261/08 (2006.01) A61K 31/42 (2006.01) C07D 261/10 (2006.01)
Patent
CA 2749677
The present invention relates to isoxazole-5-carboxamide derivative having the general Formula (I), or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising the same, as well as to the use of said isoxazole-5-carboxamide derivatives for the treatment of TRPV1 mediated disorders, such as acute and chronic pain disorders, acute and chronic neuropathic pain, acute and chronic inflammatorypain, respiratorydiseases, and lower urinary tract disorders.
La présente invention concerne un dérivé d'isoxazole-5-carboxamide ayant la formule générale (I) ou l'un de ses sels pharmaceutiquement acceptables, des compositions pharmaceutiques les renfermant, ainsi que l'utilisation desdits dérivés d'isoxazole-5-carboxamide pour le traitement de troubles médiés par TRPV1, tels que des troubles de douleurs aiguës et chroniques, une douleur neuropathique aiguë et chronique, une douleur inflammatoire aiguë et chronique, des maladies respiratoires et des troubles des voies urinaires inférieures.
Palin Ronald
Ratcliffe Paul David
Fetherstonhaugh & Co.
N.v. Organon
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