C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 261/08 (2006.01) A61K 31/42 (2006.01) A61P 35/00 (2006.01) C07D 413/04 (2006.01)
Patent
CA 2597430
The invention relates to compounds of structural formula (I); or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein Ra, Rb, and R2 are defined herein. These compounds inhibit tubulin polymerization and/or target vasculature and are useful for treating proliferative disorders, such as cancer.
L'invention concerne des composés de la formule structurale (I) ou un sel, un solvate, un clathrate et un promédicament pharmaceutiquement acceptable de ceux-ci, dans laquelle Ra, Rb, et R2 ont la notation ci-définie. Ces composés inhibent la polymérisation de la tubuline et/ou ils ciblent le système vasculaire et sont utiles pour traiter les troubles prolifératifs tels que le cancer.
Borella Christopher
Chen Shoujun
Du Zhenjian
Foley Kevin
Inoue Takayo
Gowling Lafleur Henderson Llp
Synta Pharmaceuticals Corp.
LandOfFree
Isoxazole combretastin derivatives for the treatment of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Isoxazole combretastin derivatives for the treatment of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Isoxazole combretastin derivatives for the treatment of... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1518330