Isoxazole compound, pharmaceutically acceptable salt...

Details Isoxazole compound, pharmaceutically acceptable salt... Isoxazole compound, pharmaceutically acceptable salt...

C - Chemistry, Metallurgy

07

D

C07D 413/00 (2006.01) A61K 31/495 (2006.01) C07D 261/08 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2091897

ABSTRACT OF THE DISCLOSURE Isoxazole compound represented by general formula (1), pharmaceutically acceptable salt thereof, and medicinal use thereof; wherein R represents hydrogen or lower alkoxy, and R1 represents a group represented by general formula (2) wherein A represents NH or O, B represents CH2 or CO, m represents 0 or 1, n represents an integer of 1 to 12, X reprssents H, OH or lower alkoxycarbonyl, and Y represents H or Ph which may be haloyenated: a group repre ented by general formula (3) wherein Z represents pyrimidinyl: or a group represented by general formula (4) wherein R2 represents styryl which may be hydroxylated.

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