C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/06 (2006.01) A61K 31/425 (2006.01) A61K 31/4439 (2006.01) A61P 25/28 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2759598
The present invention is concerned with isoxazole-thiazole derivatives of formula I, having affinity and selectivity for GABA A a5 receptor, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful as cognitive enhancer or for the therapeutic and/or prophylactic treatment of cognitive disorders like Alzheimer's disease.
L'invention concerne des dérivés d'isoxazole-thiazole représentés par la formule I, qui présentent une affinité et une sélectivité pour le récepteur GABA A a5, un procédé de fabrication de ces dérivés, des compositions pharmaceutiques contenant ceux-ci et l'utilisation de ces dérivés comme matières thérapeutiquement actives. Les composés actifs de l'invention sont utiles comme agents améliorant les facultés cognitives ou dans le traitement thérapeutique et/ou prophylactique de troubles cognitifs tels que la maladie d'Alzheimer.
Jakob-Roetne Roland
Lucas Matthew C.
Thomas Andrew
F. Hoffmann-La Roche Ag
Smart & Biggar
LandOfFree
Isoxazole-thiazole derivatives as gaba a receptor inverse... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Isoxazole-thiazole derivatives as gaba a receptor inverse..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Isoxazole-thiazole derivatives as gaba a receptor inverse... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1438058