Isoxazolo¬4,5-d|pyrimidines as crf antagonists

C - Chemistry – Metallurgy – 07 – D

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C07D 498/04 (2006.01) A61K 31/505 (2006.01)

Patent

CA 2339188

The present invention describes novel isoxazolo[1,5-a]pyrimidines of formula (I), wherein R is an aromatic or heteroaromatic ring, or pharmaceutically acceptable salt form thereof, which are useful as CRF antagonists.

La présente invention a trait à de nouvelles isoxazolo[1,5-a]pyrimidines représentées par la formule (I), dans laquelle R est un noyau aromatique ou hétéroaromatique, ou à une forme saline pharmaceutiquement acceptable de celles-ci, qui sont utiles comme antagonistes du CRF.

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