Isoxazolo[4,5]pyridin-3-yl-piperazin derivatives useful as...

Details Isoxazolo[4,5]pyridin-3-yl-piperazin derivatives useful as... Isoxazolo[4,5]pyridin-3-yl-piperazin derivatives useful as...

C - Chemistry, Metallurgy

07

D

C07D 498/04 (2006.01) A61K 31/437 (2006.01) A61P 25/30 (2006.01)

Patent

CA 2737252

The present invention relates to compounds of the general formula (I), having affinity and selectivity for the dopamine D3 receptors, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The active compounds of the present invention are useful for the therapeutic and/or prophylactic treatment of cognitive disorders.

La présente invention concerne des composés de formule générale (I), qui ont une affinité et une sélectivité pour les récepteurs de dopamine D3, leur fabrication, des compositions pharmaceutiques les contenant et leur utilisation en tant que médicaments. Les composés actifs de la présente invention sont utiles pour le traitement thérapeutique et/ou prophylactique de troubles cognitifs.

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