Isoxazolyl indolamines

C - Chemistry – Metallurgy – 07 – D

Patent

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260/304, 260/266

C07D 413/00 (2006.01) C07D 261/08 (2006.01) C07D 413/04 (2006.01)

Patent

CA 1163267

Abstract of the Disclosure Isoxazolyl indolamines as hypoglycemic agents and agents for inhibiting or impeding post-prandial hypoglycemia. These compounds have the formula I Image wherein R1 represents hydrogen, fluorine, chlorine, C1-4alkyl or C1-4alkoxy, R2 represents hydrogen or hydroxyl, R3 and R4 represent, independently, C1-4- alkyl or together with the adjacent nitrogen atom Image or Image wherein n is 1, 2 or 3, R5 represents hydrogen or C1-4alkyl and R6 represents hydrogen, C1-4alkyl, phenyl or phenyl mono-substituted by S fluorine, chlorine, C1-4alkyl or C1-4alkoxy.

374979

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