Itpks as modifiers of the igfr pathway and methods of use

G - Physics – 01 – N

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G01N 33/53 (2006.01)

Patent

CA 2555381

Human ITPK genes are identified as modulators of the IGFR pathway and thus are therapeutic targets for disorders associated with defective IGFR function Methods for identifying modulators of IGFR comprising screening for agents that modulate the activity of ITPK are provided.

L'invention concerne des gènes ITPK humains identifiés comme modulateurs de la voie IGFR, et constituant ainsi des cibles thérapeutiques dans les troubles associés à une fonction IGFR déficiente. L'invention concerne également des méthodes d'identification de modulateurs de l'IGFR, consistant à cribler des agents modulant l'activité des ITPK.

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