Itraconazole and saperconazole stereoisomers

Details Itraconazole and saperconazole stereoisomers Itraconazole and saperconazole stereoisomers

C - Chemistry, Metallurgy

07

D

C07D 405/14 (2006.01) A61K 31/496 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2117651

The present invention is concerned with the stereoisomeric forms of itraconazole (X=Cl) and saperconazole (X=F), which may be represented by formula (cis-(I)), and the pharmaceutically acceptable acid addition salt forms thereof, processes for preparing said stereoisomeric forms, the complexes thereof with cyclodextrin derivatives, pharmaceutical compositions com- prising said complexes and methods of preparing said complexes and pharmaceutical compositions.

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