J-chain and analogues as epithelial cell targeting conjugates

Details J-chain and analogues as epithelial cell targeting conjugates J-chain and analogues as epithelial cell targeting conjugates

A - Human Necessities

61

K

A61K 47/48 (2006.01)

Patent

CA 2306204

Targeting molecules for use in delivering biological agents to non-polarized epithelial cells are disclosed. Upon delivery, the biological agent(s) are lethal to the epithelial cell. The targeting molecules may be used, for example, for the eradication of metastatic epithelial cells.

On décrit des molécules de ciblage destinées à être utilisées pour apporter des agents biologiques à des cellules épithéliales non polarisées. Au moment de l'apport, le ou les agents biologiques sont mortels pour la cellule épithéliale. Les molécules de ciblage peuvent être utilisées par exemple pour éradiquer des cellules épithéliales métastatiques.

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