C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/12 (2006.01) A61K 31/517 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2752885
Provided herein are quinazoline compounds for treatment of JAK kinase mediated diseases, including JAK2 kinase-, JAK3 kinase- or TYK2 kinase-mediated diseases. Also provided are pharmaceutical compositions comprising the compounds and methods of using the compounds and compositions. (I).
La présente invention concerne des composés de quinazoline destinés au traitement de maladies induites par les JAK kinases, comprenant les maladies induites par la JAK2 kinase, la JAK3 kinase ou la TYK2 kinase. L'invention concerne également des compositions pharmaceutiques comprenant les composés et des procédés d'utilisation des composés et des compositions. Formule (I).
Abraham Sunny
Chao Qi
Hadd Michael J.
Holladay Mark W.
Liu Gang
Ambit Biosciences Corporation
Osler Hoskin & Harcourt Llp
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