Jak2 mutations

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/54 (2006.01) C07H 21/00 (2006.01) C12N 9/12 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2705269

Novel mutations in the JAK2 gene and JAK2 protein are disclosed. Methods and compositions useful for diagnosing or determining prognosis for an individual having a neoplastic diseases including, for example, myeloproliferative diseases are also disclosed.

La présente invention repose sur l'identification de nouvelles mutations dans le gène JAK2 et la protéine JAK2. L'invention concerne des procédés et des compositions utiles pour le diagnostic de maladies néoplasiques comprenant, par exemple, des maladies myéloprolifératives. L'invention concerne également des procédés et des compositions utiles pour la détermination d'un pronostic pour un sujet diagnostiqué comme souffrant d'une maladie néoplasique.

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