Jmy, a co-activator for p300/cbp, nucleic acid encoding jmy...

Details Jmy, a co-activator for p300/cbp, nucleic acid encoding jmy... Jmy, a co-activator for p300/cbp, nucleic acid encoding jmy...

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01)

Patent

CA 2307330

The invention provides an isolated nucleic acid (SEQ ID No:1) encoding a novel protein, JMY, which is found to be a co-activator of p300/CBP. The invention also provides JMY polypeptides and antibodies thereto, as well as assays for modulators of the cell cycle which target the interaction of JMY with transcription factors such as E2F, ER or TBP.

Acide nucléique isolé (Séq. ID No:1) codant une nouvelle protéine, JMY, qui s'est révélée être un coactivateur de p300/CBP. La présente invention concerne également des polypeptides JMY et des anticorps contre lesdits polypeptides, ainsi que des dosages à la recherche de modulateurs du cycle cellulaire qui ciblent l'interaction de JMY à l'aide de facteurs de transcription tels que E2F, ER ou TBP.

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