C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/47 (2006.01) A61K 31/401 (2006.01) A61K 31/4025 (2006.01) A61K 31/403 (2006.01) A61K 31/4035 (2006.01) A61K 31/4439 (2006.01) A61K 31/496 (2006.01) C07D 207/16 (2006.01) C07D 209/42 (2006.01) C07D 209/52 (2006.01) C07D 211/60 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07K 14/435 (2006.01)
Patent
CA 2691849
The present invention relates to the crystal structure of the serine protease kallikrein 7 and to the use of this crystal structure in drug discovery. The present invention also relates to compounds binding specifically to this active site of kallikrein 7.
La présente invention porte sur la culture cristalline de la kallikréine 7 de la sérine protéase et sur l'utilisation de cette structure cristalline dans la découverte de médicaments. Elle concerne également les composés se liant spécifiquement à ce site actif de la kallikréine 7.
Berst Frederic
Bodendorf Ursula
Ehrhardt Claus
Flohr Stefanie
Gerhartz Bernd
Fetherstonhaugh & Co.
Novartis Ag
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