C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/81 (2006.01) A61K 38/57 (2006.01) C12N 9/64 (2006.01) C12Q 1/37 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2180950
This invention relates to novel BPTI-homologous Kunitz domains, especially LACI homologues, which inhibit one or more plasma (and/or tissue) kallikreins, and to the therapeutic and diagnostic use of these novel proteins. In particular, this invention relates to Kunitz domains derived from Kunitz domains of human origin and especially to the first Kunitz domain of LACI.
Nouveaux domaines de Kunitz homologues de l'inhibiteur de la trypsine pancréatique bovine (BPTI), notamment des homologues de LACI, inhibant une ou plusieurs kallikréines plasmatiques (et/ou tissulaires), et utilisation thérapeutique et diagnostique de ces nouvelles protéines. Plus particulièrement, il s'agit de domaines de Kunitz dérivés de domaines de Kunitz d'origine humaine, et notamment du premier domaine de Kunitz de LACI.
Ladner Robert Charles
Markland William
Dyax Corp.
Protein Engineering Corporation
Smart & Biggar
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