Kanamycin c derivatives

Details Kanamycin c derivatives Kanamycin c derivatives

C - Chemistry, Metallurgy

07

H

260/230.5

C07H 15/22 (2006.01) C07H 15/236 (2006.01)

Patent

CA 1081693

NEW KANAMYCIN C DERIVATIVES ABSTRACT OF THE DISCLOSURE 1-N-(L-4-amino-2-hydroxybutyryl) derivatives of kanamycin C, 3'-deoxykanamycin C and 3',4'-dideoxykanamycin C have been pre- pared which possess high antibacterial activity against a wide variety of drug-resistant bacteria. These new derivatives are prepared by reacting L-4-amino-2-hydroxybutyric acid or a functional equivalent thereof with the l-amino group of kanamycin C, 3'- deoxykanamycin C or 3',4'-dideoxykanamycin C. -1 -

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