C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 409/12 (2006.01) A61K 31/451 (2006.01) A61K 31/453 (2006.01) A61K 31/4535 (2006.01) C07D 211/22 (2006.01) C07D 405/12 (2006.01)
Patent
CA 2598416
Kappa opioid receptor antagonists are provided that yield significant improvements in functional binding assays to kappa opioid receptors, and the use of these antagonists in treatment of disease states that are ameliorated by binding of the kappa opioid receptor such as heroin or cocaine addictions.
Antagonistes du récepteur opïoide kappa apportant des améliorations considérables dans les essais de liaison fonctionnelle à des récepteurs opïoides kappa et utilisation de ces antagonistes dans le traitement de pathologies améliorées par la liaison du récepteur opïoide kappa, notamment l'accoutumance à l'héroïne ou à la cocaïne.
Brieaddy Lawrence E.
Carroll Frank Ivy
Navarro Herman A.
Runyon Scott P.
Thomas James B.
Norton Rose Or S.e.n.c.r.l.,s.r.l./llp
Research Triangle Institute
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