Kcnb: a novel potassium channel protein

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) G01N 21/17 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2401906

The present invention provides nucleic acid and protein sequences for a novel potassium channel protein, KCNB. The herein-disclosed sequences can be used for any of a number of purposes, including for the specific detection of KCNB, for the identification of molecules that associate with and/or modulate the activity of KCNB, to diagnose any of a number of conditions associated with KCNB or KCNB activity, or to modulate the number or activity of KCNB molecules in a mammal.

La présente invention concerne de l'acide nucléique et des séquences protéiques associés à une nouvelle protéine des canaux à potassium, la KCNB. Lesdites séquences peuvent être utilisées à un certain nombre de fins différentes, y compris pour la détection spécifique de KCNB, pour l'identification de molécules qui s'associent avec et/ou modulent l'activité de KCNB, pour diagnostiquer un certain nombre d'états pathologiques associés à la KCNB ou à l'activité de la KCNB, ou pour moduler la quantité ou l'activité des molécules KCNB chez un mammifère.

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