C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 19/26 (2006.01) A61K 31/70 (2006.01) A61K 31/737 (2006.01) C07H 11/00 (2006.01) C07H 13/04 (2006.01) C08B 37/00 (2006.01) C12S 3/02 (2006.01)
Patent
CA 2206611
A keratan sulfate oligosaccharide comprising a di- to penta-saccharide which has a sulfated N-acetylglucosamine at the reducing end and wherein at least two hydroxyl groups per molecule have been sulfated, preferably one containing a disaccharide of the formula Gal(6S)-G1cNAc(6S) (wherein Gal, G1cN, Ac and 6S represent, respectively, galactose, glucosamine, acetyl and 6-0-sulfate) as the constituent; and antiphlogistic agent, antiallergic agent, immunoregulator, cell differentiation inducer and apoptosis inducer each containing the above oligosaccharide and/or a pharmaceutically acceptable salt thereof as the active ingredient.
Oligosaccharide de sulfate de kératane comprenant un di- à penta-saccharide qui comporte une N-acétylglucosamine sulfatée au niveau de son extrémité de réduction, et dans lequel au moins deux groupes hydroxyle par molécule ont été sulfatés, dont un contient, de préférence, comme constituant, un disaccharide de formule Gal(6S)-GlcNAc(6S) (Gal, GlcN, Ac et 6S représentant respectivement galactose, glucosamine, acétyle et sulfate 6-0); et un agent antiinflammatoire, un agent antiallergique, un immunorégulateur, un agent induisant la différentiation cellulaire et un agent induisant l'apoptose contenant chacun ledit oligosaccharide et/ou un sel pharmaceutiquement acceptable de celui-ci comme principe actif.
Asari Akira
Maruyama Hiroshi
Miyauchi Satoshi
Morikawa Kiyoshi
Tawada Akira
Seikagaku Kogyo Co. Ltd.
Smart & Biggar
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