Keratin-binding polypeptides

Details Keratin-binding polypeptides Keratin-binding polypeptides

C - Chemistry, Metallurgy

07

K

C07K 19/00 (2006.01) A61K 8/64 (2006.01) A61K 38/17 (2006.01) A61Q 5/00 (2006.01) A61Q 19/00 (2006.01)

Patent

CA 2563999

The invention relates to novel keratin-binding protein active substances, and also to the production and use thereof. Particularly suitable keratin-binding polypeptides are sequences which are contained in human desmoplakin or are derived therefrom by altering the human desmoplakin polypeptide sequences such as amino acid insertions, substitutions or deletions. The polypeptide sequences of the human desmoplakin is represented in SEQ ID NO: 1. A suitable keratin-binding domain (domain B) is the polypeptide sequence SEQ ID NO: 1, position 2193 2481, in addition to functional equivalents thereof. An additional keratin-binding domain (domain C) is the polypeptide sequence SEQ ID NO: 1, position 2606 2871 and the functional equivalents thereof.

L'invention concerne de nouvelles substances actives de protéine liant la kératine, leur fabrication et leur utilisation.

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