Ketolide antibacterials

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 17/08 (2006.01) A61K 31/70 (2006.01)

Patent

CA 2370743

A series of ketolide antibacterials in the macrolide family of formula (a), intermediates used in their manufacture and pharmaceutical compositions containing them. The compounds are erythromycin analogues useful in the treatment of bacterial and protozoal infections and in the treatment of other conditions involving gastric motility.

La présente invention concerne un groupe d'agents antibactériens cétolides faisant partie de la famille des macrolides correspondant à la formule (a), ainsi que des intermédiaires utilisés dans leur préparation et des compositions pharmaceutiques contenant ces derniers. Les composés sont des analogues d'érythromycine utilisés dans le traitement des infections bactériennes et protozoaires et dans le traitement d'autres pathologies impliquant la motilité gastrique.

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