Ketorolac derivatives with considerably reduced...

Details Ketorolac derivatives with considerably reduced... Ketorolac derivatives with considerably reduced...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/40 (2006.01)

Patent

CA 2113226

ABSTRACT The present invention concerns compounds of formula (I) which is the novel 2-(1-pyrrolidinyl)ethyl ester of (?)-5-benzoyl-2,3- dihydro-1H-pyrrolizine-1-carboxyl- or ketorolac-acid, the pharmaceutically acceptable addition salts thexeof, preferably oxalate. It is known that the commercially available ketorolac (trometamole salt) exhibits undesired side effects (gastro- intestinal irritation and ulceration). Surprisingly, when applying the compounds according to the invention there are considerably less undesired effects which render them potentially of great advantage as analgetic/antiphlogistic agent.

Affiliated with

Also associated with

Rating

Ketorolac derivatives with considerably reduced... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Ketorolac derivatives with considerably reduced..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ketorolac derivatives with considerably reduced... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1854896