A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/16 (2006.01) A61K 38/17 (2006.01) A61K 38/18 (2006.01) C07K 14/50 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2457781
Compositions comprising keratinocyte growth factor (KGF) polypeptides and methods of using the same are described. The KGF polypeptides of the present invention display enhanced bioactivity relative to full-length KGF163. Accordingly, the KGF polypeptides of the present invention may be used in compositions in lesser amounts than would be necessary using KGF163.
L'invention concerne des compositions comprenant des polypeptides de facteur de croissance du kératinocyte (KGF) et leurs procédés d'utilisation. Les polypeptides KGF de l'invention présentent une bioactivité améliorée par rapport aux KGF¿163? pleine longueur. Ainsi, lesdits polypetides KGF peuvent être utilisés dans des compositions à des doses inférieures à celles qu'il serait nécessaire d'utiliser avec des KGF¿163?.
Crawford Kenneth
Gospodarowicz Denis J.
Kavanaugh W. Michael
Borden Ladner Gervais Llp
Chiron Corporation
Novartis Vaccines And Diagnostics Inc.
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