Kinase inhibitors

Details Kinase inhibitors Kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 403/12 (2006.01) A61K 31/4155 (2006.01) C07D 239/553 (2006.01)

Patent

CA 2587427

Disclosed are protein kinase inhibitors of Formula Ia and Ib, compositions comprising such inhibitors, and methods of use, thereof. More particularly, these compounds and compositions are inhibitors of Aurora-A (Aurora-2) and Aurora-B (Aurora-1) protein kinase. Also disclosed are methods of using these compounds and compositions to prevent and treat diseases associated with protein kinases, especially diseases associated with Aurora-A or Aurora-B, such as cancer.

L'invention concerne des inhibiteurs de protéine kinase de formule Ia et Ib, des compositions les renfermant, et des procédés d'utilisation correspondants ; plus précisément, les composés et les compositions en question sont des inhibiteurs de protéine kinase Aurora-A (Aurora-2) et Aurora-B (Aurora-1). On décrit aussi des procédés d'utilisation correspondants pour la prévention et le traitement de maladies associées aux protéines kinases, en particulier les maladies associées à Aurora-A ou Aurora-B, comme le cancer.

Affiliated with

Also associated with

Rating

Kinase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Kinase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Kinase inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1374979